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Tuesday, 31 October 2017

Health: Breast Cancer Risk Factors You Need To Pay Attention To

Every woman wants to know what she can do to lower her risk of breast cancer. Perhaps, some of the factors associated with breast cancer such as being a woman, your age, and your genetics, cannot be changed. Apparently, other factors like being overweight, lack of exercise, smoking cigarettes, and eating unhealthy food, can be changed by making choices. By choosing the healthiest lifestyle options possible, you can empower yourself and make sure your breast cancer risk is as low as possible.

The known risk factors for breast cancer are listed below. Click on each link to learn more about the risk factor and ways you can minimize it in your own life. If a factor can't be changed (such as your genetics), you can learn about protective steps you can take that can help keep your risk as low as possible.


Being a Woman
There is no doubt that being a woman is the biggest risk factor for developing breast cancer. In America, there are about 190,000 new cases of invasive breast cancer and 60,000 cases of non-invasive breast cancer concerning women this year. While men do develop breast cancer, less than 1% of all new breast cancer cases happen in men. Approximately 2,000 cases of breast cancer will be diagnosed in American men this year.


Age
Everyone living is growing older. And perhaps with many other diseases, your risk of breast cancer goes up as you get older. For example, according to the American Cancer Society, about 1 out of 8 invasive breast cancers develop in women younger than 45. About 2 out of 3 invasive breast cancers are found in women 55 or older.

In fact, the aging process is the biggest risk factor for breast cancer. That's because the longer we live, there are more opportunities for genetic damage (mutations) in the body. And as we age, our bodies are less capable of repairing genetic damage.


Family History
Women with close relatives who've been diagnosed with breast cancer have a higher risk of developing the disease. Thus, if you've had one first-degree female relative (sister, mother, daughter) diagnosed with breast cancer, your risk is doubled. If two first-degree relatives have been diagnosed, your risk is 5 times higher than average.

If your brother or father have been diagnosed with breast cancer, your risk is higher, though researchers aren't sure how much higher.


Genetics
Apparently about 5% to 10% of breast cancers are thought to be hereditary, caused by abnormal genes passed from parent to child. Hence, genes are short segments of DNA (deoxyribonucleic acid) found in chromosomes. DNA contains the instructions for building proteins, while proteins control the structure and function of all the cells that make up your body.

Think of your genes as an instruction manual for cell growth and function. Abnormalities in the DNA are like typographical errors. They may provide the wrong set of instructions, leading to faulty cell growth or function. In any one person, if there is an error in a gene, that same mistake will appear in all the cells that contain the same gene. This is like having an instruction manual in which all the copies have the same typographical error.


Personal History of Breast Cancer
If you've been diagnosed with breast cancer, you're 3 to 4 times more likely to develop a new cancer in the other breast or a different part of the same breast. This risk is different from the risk of the original cancer coming back (called risk of recurrence).


Radiation to Chest or Face Before Age 30
If you had radiation to the chest to treat another cancer (not breast cancer), such as Hodgkin disease or non-Hodgkin lymphoma, you have a higher-than-average risk of breast cancer. If you had radiation to the face as an adolescent to treat acne (something that's no longer done), you are at higher risk of developing breast cancer later in life. The amount of risk increase depends on how old you were when you had radiation. The increase in risk is highest if you had radiation during adolescence, when your breasts were developing.


Certain Breast Changes
If you've been diagnosed with certain benign (not cancer) breast conditions, you may have a higher risk of breast cancer. There are several types of benign breast conditions that affect breast cancer risk:

Excessive growth of normal-looking cells: Doctors call this "proliferative lesions without atypia." In these conditions, cells in the ducts (the pipes of the breast that drain the milk out to the nipple) or lobules (the parts of the breast that make milk) are growing faster than normal, but the cells look normal.


Race/Ethnicity
White women are slightly more likely to develop breast cancer than African American, Hispanic, and Asian women. But African American women are more likely to develop more aggressive, more advanced-stage breast cancer that is diagnosed at a young age. African American women are also more likely to die from breast cancer. Some of these differences in outcomes may be due to less access to mammography and lower quality of medical care, as well as various lifestyle patterns (eating habits and weight issues for example) that are more common in some ethnic groups than in others. These factors can be changed and improved.


Being Overweight
Overweight and obese women, defined as having a BMI (body mass index) over 25, have a higher risk of being diagnosed with breast cancer compared to women who maintain a healthy weight, especially after menopause. Being overweight also can increase the risk of the breast cancer coming back (recurrence) in women who have had the disease.

This higher risk is because fat cells make estrogen; extra fat cells mean more estrogen in the body, and estrogen can make hormone-receptor-positive breast cancers develop and grow. Still, the link between extra weight and breast cancer is complicated and affected by other factors. For instance, the location of the extra weight matters. Extra fat around your belly may increase risk more than the same amount of extra fat around your thighs or hips.


Pregnancy History
Women who haven't had a full-term pregnancy or have their first child after the age of 30 have a higher risk of breast cancer compared to women who gave birth before the age of 30.

Apparently, when breast cells are made in adolescence, they are immature and very active until your first full-term pregnancy. The immature breast cells respond to the hormone estrogen as well as hormone-disrupting chemicals in products. Your first full-term pregnancy makes the breast cells fully mature and grow in a more regular way. This is the main reason why pregnancy helps protect against breast cancer. Being pregnant also reduces your total number of lifetime menstrual cycles, which may be another reason why earlier pregnancy seems to offer a protective effect.


Breastfeeding History
Breastfeeding can lower breast cancer risk, especially if a woman breastfeeds for longer than 1 year. There is less benefit for women who breastfeed for less than a year, which is more typical for women living in countries such as the United States. There are several reasons why breastfeeding protects breast health:
  • making milk 24/7 limits breast cells' ability to misbehave
  • most women have fewer menstrual cycles when they're breastfeeding (added to the 9 missed periods during pregnancy) resulting in lower estrogen levels
  • many women tend to eat more nutritious foods and follow healthier lifestyles (limit smoking and alcohol use) while breastfeeding

Beyond breast health protection, breastfeeding provides important health benefits to the baby and helps the bonding process.


Menstrual History
Women who started menstruating (having periods) younger than age 12 have a higher risk of breast cancer later in life. The same is true for women who go through menopause when they're older than 55. Over the past 15 years, girls have been starting puberty at younger ages. Breast development has started even earlier than menstrual periods. This unexpected shift has been attributed to the obesity epidemic and broad exposure to hormone disruptors, since a rise in hormones triggers the onset of breast development and puberty. The age when women go through menopause, however, has stayed about the same.

The earlier your breasts form, the sooner they're ready to interact with hormones inside and outside your body, as well as with chemicals in products that are hormone disruptors. This longer interaction with hormones and hormone disruptors can increase risk. Hence, when girls start menstruating at a younger age, the time between breast development and a first full-term pregnancy is usually longer than when menstruation happens later. During this time, breast tissue tends to be immature, overactive, and particularly sensitive to hormonal influences.

The longer a woman menstruates, the higher her lifetime exposure to the hormones estrogen and progesterone. All of these factors are associated with a higher risk of breast cancer later in life.


Using HRT (Hormone Replacement Therapy)
Current or recent past users of hormonal replacement therapy (HRT) have a higher risk of being diagnosed with breast cancer. Before the link between HRT use and breast cancer risk was established, many postmenopausal women took HRT for many years to ease menopausal symptoms (hot flashes, fatigue) and to reduce bone loss. However, since 2002, when research linked HRT and risk, the number of women taking HRT has dropped dramatically. Still, many women continue to use HRT to handle bothersome menopausal symptoms.


Drinking Alcohol
Research consistently shows that drinking alcoholic beverages, beer, wine, and liquor; increases a woman's risk of hormone-receptor-positive breast cancer. Alcohol can increase levels of estrogen and other hormones associated with hormone-receptor-positive breast cancer. Alcohol also may increase breast cancer risk by damaging DNA in cells.

Compared to women who don't drink at all, women who have three alcoholic drinks per week have a 15% higher risk of breast cancer. Experts estimate that the risk of breast cancer goes up another 10% for each additional drink women regularly have each day.


Having Dense Breasts
Dense breasts have less fatty tissue and more non-fatty tissue compared to breasts that aren't dense. Dense breasts have more gland tissue that makes and drains milk and supportive tissue (also called stroma) that surrounds the gland. Breast density can be inherited, so if your mother has dense breasts, it's likely you will, too. One way to measure breast density is the thickness of tissue on a mammogram.


Lack of Exercise
Research shows a link between exercising regularly at a moderate or intense level for 4 to 7 hours per week and a lower risk of breast cancer. Exercise consumes and controls blood sugar and limits blood levels of insulin growth factor, a hormone that can affect how breast cells grow and behave. People who exercise regularly tend to be healthier and are more likely to maintain a healthy weight and have little or no excess fat compared to people who don't exercise.

Fat cells make estrogen and extra fat cells make extra estrogen. When breast cells are exposed to extra estrogen over time, the risk of developing breast cancer is higher.


Smoking
Smoking causes a number of diseases and is linked to a higher risk of breast cancer in younger, premenopausal women. Research also has shown that there may be link between very heavy second-hand smoke exposure and breast cancer risk in postmenopausal women.

Smoking also can increase complications from breast cancer treatment, including:
  • damage to the lungs from radiation therapy
  • difficulty healing after surgery and breast reconstruction
  • higher risk of blood clots when taking hormonal therapy medicines


Emerging risks factors includes:
Examine yourself of breast cancer risk; early detention is far better than treatment of breast cancer. #DubemickyInspiringGreatnessDaily. Good morning, and do have yourself a wonderful day. 

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